si-mexico Chapter 293
Chapter 293
Qi Cheng turned over on the sofa, remembering that the blogger he followed who introduced the time-travel skills should have updated his video, so he quickly found it.
I guess the nobles in ancient times were also waiting anxiously.
If you find you can't make penicillin after experimenting, don't worry! Today, I'll teach you how to make allicin and berberine.
[Allicin is quite effective in sterilizing and disinfecting bacteria, though it's still a bit less potent than penicillin. However, allicin has an unparalleled advantage: the raw materials are readily available.]
Garlic originates from the highlands of western Asia and along the Mediterranean coast. It was introduced to China by Zhang Qian during the Han Dynasty and has been widely cultivated there ever since.
Daqin
Qin Shihuang shook his head helplessly. There was no such thing as garlic at that time, and it was unknown when the joint expedition team would come back.
He is still waiting for the fruits and vegetables.
"Let those doctors continue their research on penicillin. Don't slack off just because these two things have appeared!" Qin Shi Huang ordered loudly. "Whoever finds the answer will be rewarded handsomely."
big man
Liu Che laughed heartily. After the sky curtain appeared, the Han minister who was mentioned most was Zhang Qian. It seemed that he was indeed very famous in later generations.
He should be rewarded handsomely!
"Come here, add another 500 households to Zhang Qian's fiefdom, and have him take a few more people to travel south and train more envoys who can go out."
"Also, all the generals in the future must carry something like allicin with them. There must be no mistakes!"
[The production of allicin is relatively easy. We have already mentioned the high-proof alcohol required, so there is no need to go to great lengths.]
All that's left is to crush the garlic. It's important to note that the finer the garlic, the better. A particle size of 2-3 mm is ideal. After adding the alcohol, the temperature should be maintained at 20-40 degrees Celsius for about four to six hours.
[After extracting the upper layer of solution, the next step is purification and recrystallization. ]
We first pass the solution through multiple layers of filter paper to filter out any solid foreign matter. Then, we place the solution in hot ethanol. As the temperature drops, allicin will slowly precipitate out.
After a few times, you can get allicin with a relatively high purity.
[Finally, a reminder: allicin also needs to be stored in a dry, sealed, light-proof environment, preferably below 4 degrees Celsius.]
Tang Dynasty
Li Shimin thought about it and felt that this method was much simpler than making penicillin. Garlic was also easy to obtain. Most importantly, the Tang Dynasty now had experience in making alcohol.
Because several imperial concubines enjoyed making perfumes.
"Of course we have to make this. Do you have anything to say?"
Wei Zheng stepped forward and said, "Your Majesty, allicin may indeed have some effect. Many people will surely follow suit, so the price of garlic will definitely remain high."
"what do you mean?"
"The imperial court should control the price of garlic, produce garlic extract as quickly as possible, and develop detailed procedures for distributing it to the people everywhere."
Li Shimin nodded, thinking that Wei Zheng’s suggestion was very good.
Qing Dynasty
Heshen, who was not with Qianlong, laughed out loud. When the topic of allicin was brought up from the sky, he arranged for people to go to the city to buy garlic. Now he was going to make a fortune.
He won't make a move unless the price increases tenfold.
"Liu Quan, how's the task assigned to you going? Can you find any big fish over at Yuquan Mountain? We also need to continue harvesting garlic. Besides the capital, we also need to visit Tongzhou."
……
[After talking about allicin, let’s talk about berberine. ]
Coptis chinensis is a traditional Chinese medicinal herb. It was mentioned as early as the Three Kingdoms period in Zhang Zhongjing's Treatise on Febrile Diseases. In Traditional Chinese Medicine, it is generally used to clear heat and detoxify, and can be taken internally or applied externally.
[Of course, it is also very effective in antibacterial issues. ]
The berberine we extract today doesn't require the traditional boiling method, but rather alcohol. First, we crush the root of the coptis root, then add a high concentration of alcohol.
After soaking for several days, you can wrap it in gauze and take out only the liquid inside. Then heat it slightly to allow the alcohol to evaporate. What remains is the berberine we need.
[When storing, be sure to keep the environment cool and dry. You can store it in a cave because the temperature inside is relatively stable.]
Ming Dynasty
The two substances introduced by Tianmu are both easy to extract, at least much simpler than penicillin, but Zhu Yuanzhang did not want to give up penicillin, so he asked the Imperial Hospital in charge to make it.
At the same time, an order was issued prohibiting others from selling these two medicines.
Zhu Yuanzhang had already made up his mind. Tianmu showed that the Ming Dynasty did not invest enough in the army. From now on, the money from selling these three medicines would be invested in the army.
"Father, I went to see them a few days ago. The Imperial Hospital is still very confident in developing penicillin! But they still need some silver to make the equipment."
"Humph, you haven't seen anything yet, and you want money first."
"A big reward always brings out the brave."
Great Sui
Yang Jian did not arrange for anyone to take the video until it was finished. After several ministers learned about it, they rushed to the palace to persuade him. This was a matter concerning human life, so how could he not take it seriously?
"Actually, it's still a question of succession!" Yang Su stopped the ministers at the palace gate. "Don't enter the palace. It's a waste of effort."
"What does this have to do with the heir?"
Yang Su explained to them that the emperor had known about the demise of the Second Emperor of Sui Dynasty long ago and had killed Prince of Jin Yang Guang, but Crown Prince Yang Yong still did not catch the eyes of the emperor and empress.
As for the other children, they are not that promising either.
Moreover, Empress Dugu did not allow him to favor other concubines at will.
Several ministers then understood that the emperor was afraid that the Sui Dynasty would pave the way for future dynasties after it developed the technology. However, in order to live longer in the future, he said that he had thought of a good way to persuade the emperor.
"What good ideas do you have?"
"The method is not passed on to others, but I learned it from the sky."
........
After watching the video, Qi Cheng thought about it carefully in his mind. Before penicillin, there was an anti-inflammatory drug. For the imperial court at that time, this drug was also very difficult to produce.
According to the information we received, this drug was called sulfonamide, and it seemed to be something extracted from dye. Because industrialization had just started at that time, the price of this drug was very expensive.
I wonder if this blogger will teach you how to extract it.
Sulfonamide is an anti-inflammatory drug, and its effect should be stronger than allicin and berberine.