si-mexico Chapter 286
Chapter 286
After making himself a makeshift dinner, Qi Cheng carefully searched for the videos he liked to watch and discovered that the blogger who wrote the video about essential skills for time travel had finally updated it today.
[A must-have skill for time travel—the production of antibiotics.]
When your territory is large enough and the population increases, you'll need to find ways to prevent various diseases. Traditional Chinese medicine is useful, but it's slow to take effect.
[At this point, you need to research the production of antibiotics. There are many different antibiotics available, but penicillin is the easiest to produce and is very effective.]
[It is very effective for various inflammations.]
When it first came out, it was called penicillin. It was worth the same as gold, so most people probably weren't qualified to use it.
big man
Liu Che quickly realized the importance of this antibiotic, but he was now worried about whether the Han Dynasty's level was sufficient. If it could not be produced, this opportunity would be wasted.
"Shaofu, record every word the host says." Liu Che thought for a moment, "Bring a few death row prisoners from Hedong. You can find the rest of the supplies yourselves."
Tang Dynasty
Li Shimin carefully looked through the previous records and found that the host seemed to have taken this medicine when he had a cold before. It was still being used in later generations, so it must be very effective.
Datang must create it!
He needs this medicine to help him defeat the Turks and Tubo.
.......
Let's discuss this in detail. First, we need to find the source of the bacteria. Anything with green mold can be considered a source of penicillin.
[However, we prefer to use bacteria from citrus peels because the bacteria there are relatively cleaner.]
Next comes the preparation of culture medium, which requires the preparation of four aspects: carbon source, nitrogen source, inorganic salts, and growth factors.
Carbon source: In principle, anything rich in sugar can be used as a carbon source. For example, grind grains and cook them into a thick juice; the starch in it can provide a carbon source. Sugarcane juice can also be used directly, as long as the bagasse is slightly filtered.
[Nitrogen source: Protein can provide a nitrogen source for Penicillium. For example, soybean meal or peanut meal can be used. Fish meal is also acceptable. Fish meal is relatively cheap in coastal areas.]
[Inorganic salts: Inorganic salts are relatively simple. Table salt and sodium chloride can provide sodium and chlorine, potassium can be obtained from wood ash, and calcium can be directly calcined from shells.]
【Growth factors: You can use juice squeezed from vegetables and fruits. 】
Daqin
Qin Shi Huang looked at the raw materials and thought that the Qin Dynasty should be able to gather them all, so the medicine should be able to be made. However, the Mohist school was also very busy.
I don’t know which school of thought I should look for.
"Your Majesty, I think you should just give it to the doctor. It's just a medicine anyway, and they'll need their cooperation after it's prepared."
"Well, that's it."
Ming Dynasty
Zhu Di looked at these materials and wondered how the brains of later generations could be developed to cultivate the necessary bacterial sources from so many things.
"This meal is almost in your mouth. The imperial physician must find a way to get it out. Otherwise, don't blame me for being ruthless and exiling everyone to Lingnan."
Several imperial doctors didn't dare to breathe.
The emperor at this time was not joking. Exiling him to Lingnan was considered a good idea, but if he was not careful, he would lose his head.
After finishing all these things, we will synthesize the culture medium. The first step is to create a sterile environment as much as possible, and the second step is to boil the necessary utensils in water.
Then expose it to the sun.
[The pH of the culture medium also needs to be adjusted. The desired value is approximately between 6 and 7. However, there were no test strips in ancient times, so we have to use the petal indicator method.]
[Morning glory and rose are both acceptable. You can experiment a little to see what colors the acid and alkaline solutions produce.]
【This is the simplest chemistry experiment. 】
[The specific ratio of the culture medium needs to be tested by yourself, generally the carbon source and nitrogen source are more.]
[After the culture medium is ready, we need to heat it over low heat. Do not let the solution boil violently, but of course we cannot not heat it.]
[After burning, it is then exposed to the sun. These two steps are to remove other bacteria in the solution.]
[After everything is ready, add the bacterial source and incubate at 25 degrees Celsius for about seven days.]
……
Seeing that the curtain had not yet finished, most of the people in front of the curtain gave up recording. This thing was too complicated, and they simply couldn't do it under their conditions.
Let’s go into the mountains to collect herbs.
The Imperial Hospital that received the task also felt overwhelmed. There were too many steps involved. If any step was wrong, all the previous efforts would be wasted.
And I'm afraid I can't even save my own head.
Could Tianmu introduce a simple method next time?
They only have one life.
After seven days, when Penicillium has multiplied significantly, further extraction can be performed. This step requires the use of activated carbon, so I've written down the method for its production.
【This shouldn't be difficult.】
Now we're ready to start the extraction. The first step is to find a funnel and a small jar, stuff cotton into the bottom of the funnel, and then slowly pour the solution into the funnel.
We then add three times the volume of rapeseed oil to the resulting solution. After thorough stirring, three layers will form. We only need the bottom layer.
Add the following solution to the activated charcoal powder until all the liquid is absorbed.
【Then add a little distilled water to the activated carbon, then add acidic water and alkaline water, and then filter the liquid with a cotton funnel. 】
[As for how to test it, you can use animals or other bacteria. Finally, I have to mention that some people are allergic to penicillin, so it could be dangerous.]
[If you think penicillin is too difficult, we will introduce the simpler allicin and berberine in the next issue.]
……
Several imperial doctors looked at the emperor with burning eyes, saying, "Why don't we just give up on this penicillin and wait for the simpler allicin."
Tang Dynasty
"No, the sooner we make it, the more lives our Tang soldiers will have. But we haven't found cotton yet. Let those people in the Western Regions hurry up, they're waiting for it!"
"Your Majesty is wise," Changsun Wuji said with a bow. "However, I think there is one more thing to note. The preparation and extraction of the culture medium must be carried out separately, and all the formulas need to be kept in the palace."
"The formula is one thing, but we also need to pay close attention to the materials."
Li Shimin nodded. Those aristocratic families were still obedient now, but their human nature must not be tested. If the Turks gave too much money, they might leak the secret.